The Buffalo Bills stayed out west this week instead of traveling across the country twice in seven days. They have been thrashed in back-to-back games against upper echelon opponents but this trip to Arizona to face the Cardinals could be just what the doctor ordered.

Despite their 4-1 record, the Cardinals are vulnerable in key places. Buffalo is still looking for their first win on a three-hour time difference since 2004. Buffalo has given up 1200 yards and 90+ points in the last two weeks but the Cardinals throw out their back-up quarterback, third-string running back, and an offensive line that surrendered 15 sacks in two weeks.

Buffalo Bills (2-3) at Arizona Cardinals (4-1)

• Game time: 4:05 PM ET
• Location: University of Phoenix Stadium, Glendale, AZ
  
• Television: CBS affiliates in Arizona, most of Upstate New York and NW Pennsylvania
• Announcers: Bill Macatee and Steve Tasker
• Radio: Buffalo Bills Radio Network, WGR 550 AM in Buffalo, WGR550.com streaming over the web
• Web: NFL Game Center
• Odds: Cards by 3.5