The Buffalo Bills (4-6) and Indianapolis Colts (6-4) face off today in Indiana for much more than just one win. In the muddled AFC playoff picture, this game could further muddy the waters with a Buffalo win and inch the Bills closer to that elusive playoff birth.

For Bills fans, it's also an opportunity to witness what a highly touted rookie quarterback can do. Andrew Luck has been setting rookie passing marks since being the first overall draft pick. The Bills have never selected a quarterback with their first pick in the draft.

Buffalo Bills (4-6) at Indianapolis Colts (6-4)

• Game time: 1:00 PM ET
• Location: Lucas Oil Field, Indianapolis, IN
  
• Television: CBS affiliates in most of Upstate New York and parts of New England, Indiana and surrounding states
  
• Announcers: Marv Albert, Rich Gannon
  
• Radio: Buffalo Bills Radio Network, WGR 550 AM in Buffalo, WGR550.com streaming over the web
• Web: NFL.com Game Center
• Odds: Colts by 3.5