The Buffalo Bills host the New England Patriots today. The last time Bill Belichick's boys were in Buffalo, the Bills snagged their first win in 16 tries. They haven't beaten the Patriots in consecutive seasons since 2000-2001.

Both Bills running backs are listed as questionable. Fred Jackson appears more ready to return from his Week 1 knee injury than C.J. Spiller, who injured his shoulder seven days ago. Jackson will wear a knee brace and expects to be sore on Monday, but said he will play. Leodis McKelvin sat out one day of practice with a sore groin, but practiced fully on Thursday and Friday. Ruvell Martin is out.

The Patriots have a much more extensive list of injuries led by Logan Mankins, Aaron Hernandez and Julian Edelman, who have all been declared out. Brandon Deaderick also did not practice much this week, while Alfonzo Dennard, Justin Francis, Kyle Love, Nick McDonald, Sterling Moore, Shane Vereen and Sebastian Vollmer were all limited on Friday and listed as questionable. Rob Gronkowski is also listed as questionable after a hip injury cropped up on Friday, but he is expected to play.

Buffalo Bills (2-1) vs. New England Patriots (1-2)

• Game time: 1 PM ET
• Location: Ralph Wilson Stadium, Orchard Park, NY
• Television: CBS affiliates in most of the Eastern Seaboard, Oklahoma, and North-Central US
• Announcers: Greg Gumbel and Dan Dierdorf
• Radio: Buffalo Bills Radio Network, WGR 550 AM in Buffalo, WGR550.com streaming over the web
• Web: NFL Game Center
• Odds: Patriots by 4