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Bills vs. Patriots Injury Report: C.J. Spiller, Fred Jackson Both Questionable

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Buffalo Bills running backs C.J. Spiller (shoulder) and Fred Jackson (knee) are both listed as questionable for Sunday's Week 4 home game against the New England Patriots.

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After both players practiced on Friday, Buffalo Bills running backs C.J. Spiller and Fred Jackson have been officially listed as questionable for Sunday's home contest with the New England Patriots - and according to head coach Chan Gailey (via WGR 550's Joe Buscaglia), both have a "legitimate" chance of suiting up.

According to CBSSports.com's Mark Ludwiczak (via Twitter), Jackson "sounded optimistic" that he'll be able to play Sunday, telling reporters that the only way he'd sit out is if "something freaky" happens causing a setback. In the likely event that he does play, Jackson is expected to wear a knee brace to help protect his still-healing sprained LCL suffered in Week 1.

As for Spiller, the general feeling all week has held that it'd be surprising if he played, but he's also practiced for two straight days, lending credence to the idea that he may be able to suit up, after all. How he makes it through the weekend, and whether or not the team's training staff believes his injured shoulder can sustain contact, will go a long way toward determining his availability (and the breadth of his role, as well). Just don't count him out yet.

Knowing that both Jackson and Spiller are not at 100 percent, it's expected that Tashard Choice will also have a role to play on Sunday, perhaps even if both dinged stars play.