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Bills-Browns final score: Buffalo loses more than a game, 37-24

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The Buffalo Bills lost another game, but that might not be the worst thing they lost Thursday night.

Ron Schwane-USA TODAY Sports

The Buffalo Bills lost E.J. Manuel in the third quarter and weren't able to mount an offensive surge following the loss of their starting quarterback. Jeff Tuel wasn't able to lead a comeback as Buffalo lost 37-24 on Thursday night.

The Bills sped out to a 10-0 lead in the first quarter but Cleveland took a 17-10 lead in the second quarter after two great punt returns by Travis Benjamin including a touchdown. Willis McGahee punched in a score in the second quarter, as well, as the Browns ran out to 17 straight points.

Stevie Johnson and Manuel left the game in the third quarter. After a Fred Jackson touchdown to cap a drive in which Manuel went down to a knee injury, the Bills couldn't score again and that was the difference in the game. A late fourth quarter Tuel pick-six sealed the deal for Cleveland.

Buffalo gets 10 days off before facing the Cincinnati Bengals next Sunday. Hopefully, they will get Stephon Gilmore and Jairus Byrd back for that game but the status of Manuel and Stevie Johnson will be hot topics for the next week.