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Bills-Jaguars final score: Buffalo outlasts Jacksonville, 27-20

Things were ugly early and hairy late, but the Bills picked up their second road win of the season on Sunday in Jacksonville.

Melina Vastola-USA TODAY Sports

EJ Manuel threw for two touchdowns and added a third on the ground, and the Buffalo Bills forced four turnovers in a 27-20 win over the Jacksonville Jaguars. The win puts the Bills at 5-9 on the season, and gives them their second road win of the 2013 season.

Things started slowly for the Bills, who looked brutal offensively early as the Jaguars opened up a 10-3 lead. Manuel threw an interception in that stretch, but responded with a big second quarter, hitting Robert Woods for a seven-yard touchdown and running one in from eight yards out on a quarterback keeper to help the Bills open up a 20-10 halftime lead.

Bolstered by a running game that re-discovered its legs against one of the league's worst run defenses - Buffalo ran for 198 yards on the day - Manuel utilized the play-action pass deftly throughout the afternoon. After the Jaguars reeled off 10 straight points to even the score at 20 in the fourth quarter, Manuel guided the Bills down the field and hit Frank Summers on a two-yard score to provide the decisive points of the game.

The Bills forced several fumbles on the day; Nickell Robey recovered one of them, and an Aaron Williams strip of Denard Robinson negated a certain Jags touchdown, yielding a Bills touchback instead. Williams also intercepted Chad Henne in the first quarter; Henne would toss another one, late in the fourth quarter deep in Bills territory to Stephon Gilmore, to seal Jacksonville's fate.

Buffalo has a couple of injuries to deal with this week - Williams left early with a rib injury, and Marcell Dareus also didn't finish with an ankle ailment - and those will be the predominant story lines as the Bills return to the practice field this week to take on the suddenly-relevant Miami Dolphins at home.