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Sit these Buffalo Bills players
E.J. Manuel or Jeff Tuel. It's looking like Manuel will get the start at quarterback, but let's face it - you probably don't own either of these players, and with good reason. Until further notice, Buffalo's quarterback situation is a complete unknown, and unknowns are a no-go in fantasy.
Fred Jackson. Spiller is the alpha dog at running back right now, and while Jackson is certainly a sensible handcuff, it's not clear how big a role he'll have now that he's technically a reserve again.
Stevie Johnson, Robert Woods, T.J. Graham and Marquise Goodwin. These are the four receivers that will play, but the quarterback situation makes them a tough sell - Johnson for your starting lineup and the other three for your roster - for the time being. That's true even as there will be opportunities to make plays in the passing game against the New England Patriots' defense.
Scott Chandler. If there's a Bills pass-catcher to play, it's Chandler, the safety valve for a young quarterback. He had two very productive days against New England in 2012, spreading out nine receptions, 127 yards and three touchdowns over two contests. Still, the young quarterback limitation applies.
Dustin Hopkins or Dan Carpenter. Whichever man handles the Bills' placekicking duties on Sunday, there's no guarantee that he'll have many scoring opportunities.
Defense and Special Teams. Come on, now. Tom Brady is going to have a field day against Buffalo's banged up secondary, new receivers and new Bills scheme notwithstanding. Plus, the Patriots have run all over the Bills for years, so expect a big day for Stevan Ridley, too.
Start these Buffalo Bills players
C.J. Spiller. You invested a first-round pick in the guy, after all, and he's going to get the ball a lot.
... and that's it. It's Spiller or bust in Bills fantasy land this week.