Starting cornerback Leodis McKelvin is sitting out a second straight preseason game as he recovers from offseason surgery, but fellow starter Stephon Gilmore, who missed the Hall of Fame Game as well, will be back in the lineup.
Strong safety Da'Norris Searcy is active, but it's unclear how much he'll play having been excused from the team earlier this week to attend to a family emergency. That could mean a big opportunity for second-year pro Duke Williams, with whom Searcy is competing for a starting job. Undrafted rookies Derek Brim and Kenny Ladler are also not playing tonight, which should at least increase Williams' playing time.
The Bills will be without two tackles, as well: starter Cordy Glenn and reserve Edawn Coughman. That will likely mean plenty of extra snaps for rookies Cyrus Kouandjio and Seantrel Henderson, and it will probably also mean that Chris Hairston will see reps on the outside for a second straight week, rather than at right guard.
Marcell Dareus tweaked a hamstring in practice this week, but he's also active tonight, though again, how much he'll play remains to be seen.