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LeSean McCoy out for Buffalo Bills vs. Patriots, per reports

The Bills will be without their top running back in the biggest game of the season.

The Buffalo Bills won’t have LeSean McCoy in the backfield today as they face the AFC East-leading New England Patriots to finish the first half of their season. That according to a pair of reports from national media in the know.

McCoy reaggravated his hamstring in the team’s Week 7 loss to the Miami Dolphins. He initially injured it during practice on Wednesday the 19th but told reporters he felt nearly 100% and ready to play before taking on Miami.

Buffalo will roll out Mike Gillislee as their lead back today but expect to see Reggie Bush get some work on passing downs and rookie Jonathan Williams thrown in there from time to time.

The roster moves made this week seem to indicate that Robert Woods, Buffalo’s starting wide receiver, should be back in the lineup. In addition, it appears fullback Jerome Felton is close to 100% after being limited before the Miami game.