Buffalo Bills injury report: Cordy Glenn, Zay Jones out against New Orleans Saints

The Buffalo Bills (5-3) have won their first four home games for the first time in 22 years, but if they are to extend that streak to five, the Bills will have to do it without a pair of key offensive contributors.

On Friday morning, first-year head coach Sean McDermott ruled out rookie wide receiver Zay Jones (ankle) and starting left tackle Cordy Glenn (ankle) for Sunday’s 1 p.m. ET showdown with the New Orleans Saints (6-2). It’s not surprising that Glenn and Jones will be unavailable, as both missed the previous two practice sessions this week.

Despite tight end Charles Clay (knee) participating fully in Thursday’s practice, McDermott said he is questionable for Sunday’s game. Same goes for starting cornerback E.J. Gaines (hamstring).

Left tackle Seantrel Henderson (back) is also questionable, leaving the Bills with Dion Dawkins as Glenn’s replacement. While McDermott is “hopeful” that Henderson can give it a go, Conor McDermott might be pressed into action as the team’s backup tackle should Henderson’s back keep him out of the game.

As for Jones’ replacement, Jordan Matthews is healthy and Kelvin Benjamin should be able to step into a role following his trade to the team last week. Deonte Thompson could see his role expanded as could Andre Holmes.