Spikes left the practice field early in the session with a knee injury, then was spotted on the sidelines riding a stationary bike surrounded by trainers. He ultimately returned to practice, though was still listed as a limited participant on Thursday. The Bills are already thin at linebacker, so it's obviously vital that Spikes be able to play on Sunday.
The news sounds a bit more concerning for Dixon, who left practice early with a hamstring tweak and, unlike Spikes, was unable to finish the session. The free agent signing from San Francisco profiles not only as the third running back - perhaps even a short-yardage specialist - but as a key member of the team's special teams units, as well. The team still has Bryce Brown behind C.J. Spiller and Fred Jackson, so the special teams concern might be a higher priority for the team.
Rookie wide receiver Sammy Watkins (ribs) practiced in full again, as did two more players that were limited on Wednesday: cornerback Stephon Gilmore (groin) and reserve linebacker Randell Johnson (ankle).
Jonathan Meeks (neck) was once again limited; he has not played since the Bills' second preseason game. For a second straight day, tight end Lee Smith (toe) did not practice. The odds that Buffalo's run-blocking tight end will be available against the Bears appear to be small.