The Buffalo Bills are not done adding players to their roster - they currently employ 78 players, and there are still (officially announced) undrafted free agent signings and post-June 1 cut possibilities to consider - but now that the 2016 NFL Draft is complete, today is a good time to re-assess the team's depth chart.
Nothing in the below depth chart is official; it's just our projection. Again, it does not include reported undrafted free agent signings. Players whose names appear in bold are newcomers to the Bills organization since the end of the 2015 regular season. There are, by our count, 21 such names, and the seven with asterisks are the team's draft picks. Also, unconfirmed UDFA signees are not on this depth chart.
Where do you believe the team's roster is weakest as it stands today?
| Pos. | Starter | Backup | Reserve | Reserve | Reserve | Reserve |
| WR | R. Woods | G. Salas | M. Easley | L. Hankerson | J. Boykin | |
| LT | C. Glenn | S. Henderson | ||||
| LG | R. Incognito | R. Groy | ||||
| C | E. Wood | F. Velasco | R. Patrick | |||
| RG | J. Miller | C. Richardson | ||||
| RT | J. Mills | C. Kouandjio | ||||
| TE | C. Clay | J. Dray | C. Gragg | N. O'Leary | B. Annen | |
| WR | S. Watkins | M. Goodwin | K. Listenbee * | D. Lewis | G. Little | W. Powell |
| QB | T. Taylor | E. Manuel | C. Jones * | |||
| FB | J. Felton | |||||
| RB | L. McCoy | K. Williams | M. Gillislee | J. Williams * | J. Wilder, Jr. | |
| Pos. | Starter | Backup | Reserve | Reserve | Reserve | Reserve |
| ER | S. Lawson * | I. Enemkpali | L. Alexander | J. Wynn | L. Edwards | |
| DL | K. Williams | C. Bryant | J. Worthy | |||
| DL | M. Dareus | A. Washington * | T. Barnes | |||
| ER | J. Hughes | M. Lawson | R. Johnson | M. Valles | C. Reed | |
| MB | P. Brown | K. Reddick | ||||
| WB | R. Ragland * | Z. Brown | ||||
| CB | R. Darby | C. White | K. Seymour * | |||
| NB | N. Robey | S. Moore | J. Arenas | M. Noel | ||
| S | C. Graham | R. Blanton | C. Anderson | J. Dowling | ||
| S | A. Williams | D. Williams | J. Meeks | P. Thomas | ||
| CB | S. Gilmore | M. Butler | S. Seamster | |||
| Pos. | Starter | Backup | Reserve | Reserve | Reserve | Reserve |
| K | D. Carpenter | J. Gay | ||||
| P | C. Schmidt | |||||
| LS | G. Sanborn |