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Bills vs. Lions 2014 practice report: Kyle Williams, Nigel Bradham injuries bear watching

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The Buffalo Bills began their Detroit Lions prep work without two key defensive starters on the field - and there are no clear indications either way regarding their availability for Sunday.

Kevin Hoffman-USA TODAY Sports

Two key Buffalo Bills starters on defense missed practice on Wednesday as the team began preparations for Sunday's road game against the Detroit Lions.

Defensive tackle Kyle Williams, who left last week's loss to Houston early with a knee injury, was a non-participant today, though several reporters did spot him walking around the facility. Buffalo would clearly love to have arguably their most important defender on the field against a very talented Lions offense, but it's sounding like that may not ultimately be the case.

The other missing starter was linebacker Nigel Bradham, who was spotted wearing a knee brace and working with trainers prior to today's practice session. Bradham was injured on the first play of the second half against Houston, on which he intercepted a tipped Ryan Fitzpatrick pass.

Bills head coach Doug Marrone, in typical fashion since the start of 2014 training camp, was incredibly vague on the potential availability (or lack thereof) for both Williams and Bradham.

If Williams can't play in Detroit, Corbin Bryant and Stefan Charles would be next in line for more playing time, while rookie Preston Brown would be back into an every-down role if Bradham can't go.