Wynn injured his knee during Sunday's loss to Kansas City, and was never particularly likely to play tomorrow given the short work week. Buffalo planned ahead for his unavailability, promoting rookie defensive end Bryan Johnson to the active roster on Wednesday; he'll serve as the fourth end in Miami.
Four more players are listed as questionable for the contest, including running back Fred Jackson (groin) and three key special teams figures: receivers Marcus Easley (knee) and Marquise Goodwin (ribs), and cornerback Ron Brooks (groin). Easley and Brooks both missed the Kansas City loss due to their injuries, while Goodwin left after just nine snaps on offense and 17 on special teams. It's probably fair to expect all four players to be game-time decisions tomorrow.
One last player made the injury report: rookie receiver Sammy Watkins, who was questionable last week with a groin injury. He ended up playing 68 of 73 snaps against Kansas City, however, and has progressed to the point that he is probable (read: pretty certain) to play in Miami.
On Miami's side of the coin, starting cornerback Cortland Finnegan (ankle) has been ruled out, while guard Daryn Colledge (back) is doubtful. The team is also preparing for their first game without tackle Branden Albert, who landed on season-ending IR this week.