The only starter guaranteed to miss the game for Buffalo is Kyle Williams, who still isn't practicing yet following his Week 6 knee injury. The biggest remaining question is the status of the right tackle position. Cyrus Kouandjio came up with a knee injury before the Miami game, and has mostly been riding the exercise bike in open practices. Seantrel Henderson came down with an untimely illness on a short week, and if he's over that, he should be good to start tonight. If neither player is healthy enough to start, the job will go to the recently-signed Jordan Mills, who started most of the last two seasons in Chicago (albeit as one of Pro Football Focus' lowest-graded tackles).
Here's the Bills' full injury report:
The Jets, on the other hand, are dealing with a number of injuries to starters. Right guard Willie Colon was sent to IR with a knee injury, which allowed the team to activate cornerback Dee Milliner from the injury list. That part is a small silver lining, because they are likely down three starters in the secondary. Both of their starting safeties were declared out, and Antonio Cromartie is doubtful, giving him a strong chance to miss his first NFL game. Also unlikely to play is running back Bilal Powell, and another member of the secondary, Buster Skrine, is questionable - though he should still be active, if nothing else, due to the limited numbers available otherwise.
On the bright side for the Jets, Ryan Fitzpatrick was able to play through his thumb injury last week, and will do so again tonight before going in for surgery after the game. They should also have center Nick Mangold back; while he was out, the team struggled tremendously in the running game.
This is the Jets' full injury report: