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Bills vs. Eagles injury report, 2015 NFL Week 14: Stephon Gilmore, Nigel Bradham out

The Bills will be lacking starting defenders Stephon Gilmore and Nigel Bradham when they take on the Eagles this Sunday. Karlos Williams will miss his second straight game, as well.

The Buffalo Bills ruled four players out for Sunday's game against the Philadelphia Eagles due to injury, including starting cornerback Stephon Gilmore and linebacker Nigel Bradham.

Gilmore did not practice all week due to a shoulder injury suffered last Sunday against Houston. The corner who replaced him in that game, Ron Brooks, has also been ruled out as he continues to work his way back from a concussion. That means that veteran Leodis McKelvin will start alongside star rookie Ronald Darby at cornerback. Bradham, meanwhile, will probably be replaced by a combination of Manny Lawson, Kevin Reddick, and undrafted rookie A.J. Tarpley.

The fourth player ruled out: rookie running back Karlos Williams, who will miss his second straight game with a shoulder injury, and his fifth of the season. Mike Gillislee will serve as the primary backup to starter LeSean McCoy, then, for a second straight week.

In a spot of better news, starting right guard John Miller - listed as questionable with a high ankle sprain - is expected to play, at least by Rex Ryan. That will also hold true for the four players listed as probable: Chris Hogan, Charles Clay, Seantrel Henderson, and Mario Williams.