Buffalo Bills open Rex Ryan era with 27-14 win over Indianapolis Colts

#BRLive: Bills-Colts video preview

It's Bills vs. Colts week, y'all. Come get amped up for the season opener as we talk about the game with Ben Lamers from StampedeBlue.com in our weekly video preview.

No live reps for Taylor (yet) with three big names

When Tyrod Taylor leads the Buffalo Bills' offense onto the field on Sunday against Indianapolis, he'll be taking his first snaps in a live-game situation with LeSean McCoy, Sammy Watkins, and Percy Harvin.

Bills re-sign Cassel, name him No. 2 QB

As it turns out, the Buffalo Bills will have a veteran backup behind Tyrod Taylor this season, after all - and at a significantly reduced price, to boot.

Bills finalize Week 1 roster, practice squad

In need of a defensive lineman while Marcell Dareus is suspended, the Bills finalized their Week 1 roster by re-signing veteran defensive tackle Andre Fluellen on Monday.

Diamond mouthguard report discredited by Taylor

Not only is Tyrod Taylor not wearing a diamond-studded mouthguard in his starting debut with the Bills, he may not wear any sort of mouthguard at all.

New jersey numbers for Karlos Williams, Matthew Mulligan

Bills will honor AFL champs in Week 1 vs. Colts

The Buffalo Bills' 1964 and 1965 AFL championship teams will be honored on the 50th anniversary of their accomplishment during the Bills' Week 1 showdown with Indianapolis.

Karlos Williams expects to play in Week 1

McKelvin to miss at least first six games

After missing all of training camp in a cast and on a scooter, Leodis McKelvin will begin the season on Reserve/NFI, meaning that he won't play in at least six Bills games this year.

Rex Ryan is pretty mad about missed field goals

Dan Carpenter missed three field goals and an extra point in three Buffalo Bills preseason games, and head coach Rex Ryan doesn't care who knows how mad he is about it.

Report: Bills concerned about McCoy in Week 1

Even if LeSean McCoy is able to play for the Buffalo Bills in Week 1, it's sounding an awful lot like he won't be 100 percent as the Bills take on the Indianapolis Colts.

Taylor named Bills' starting QB

After a full training camp and three full preseason games, Rex Ryan has finally decided on a starting quarterback for the Bills: Tyrod Taylor.

Ryan: Goodwin may have broken ribs

Marquise Goodwin can't catch a break: a hard hit in Saturday's preseason game has likely left him with broken ribs.

Gilmore suffers shoulder injury vs. PIT

Buffalo's secondary took a hit in the first quarter as their top cornerback suffered an injury making a tackle.

Colts' Mathis wants to play vs. Bills

The Colts' best pass rusher, Robert Mathis, wants to play against the Bills in Week 1, despite only having just been activated following a year-long Achilles recovery. Will he make it?

Taylor has winning traits as passer

Through two preseason games, Tyrod Taylor has shown that he has the pocket presence and passing ability traits to be a winning quarterback for the Buffalo Bills.

Schefter: Shady expected to play Week 1

It's still unclear how severe LeSean McCoy's hamstring injury really is, but at bare minimum, he'll be ready for the Bills' season opener against Indianapolis, per ESPN's Adam Schefter.

LB Powell may have ACL injury

The Buffalo Bills lost linebacker Ty Powell to a serious-looking knee injury during Monday's practice, and it sounds like he could be out for the year with a possible ACL injury.

Rex: Wynn injures ACL, could miss 2015 season

Backup Bills defensive lineman Jarius Wynn seriously injured his ACL in the preseason opener, per Rex Ryan, and will likely miss the entirety of the 2015 season.

McKelvin may miss start of regular season

Leodis McKelvin is still wearing a protective boot on his ankle and driving a golf cart around at training camp - and the Bills sound like they're bracing themselves to start the season without one of their starting cornerbacks.

Boobie could miss a month with calf injury

It doesn't sound like the Bills will have veteran running back Boobie Dixon at their disposal for the foreseeable future, as he could miss up to a month with a calf injury.

Kromer suspended six regular season games

The Buffalo Bills have suspended Aaron Kromer for the first six games of the 2015 regular season, but he will retain his job as Bills offensive line coach - and he'll report to training camp soon.

Dareus suspended for one game in 2015

Just like last year, the Bills will be without a key defender for their season opener: last year, it was Nigel Bradham, and this year, it'll be Marcell Dareus.