LeSean McCoy injury: Buffalo Bills RB "ready to roll" in Week 1

After missing three preseason games with a hamstring issue that threw his status for Week 1 into doubt, it's sounding an awful lot like Buffalo Bills running back LeSean McCoy will be playing - and playing a lot - during this weekend's season opener against the Indianapolis Colts.

"Yeah, I think he's going to be ready to roll," head coach Rex Ryan said on Wednesday (via The Buffalo News). "We'll see how it progresses during the week. He's practicing full. So he'll be ready."

When asked if McCoy would be deployed on a "pitch count," implying that he won't be playing at full health and therefore not taking as many snaps as possible, Ryan evaded the question, but also did not seem overly concerned.

LeSean McCoy on a pitch count? Rex Ryan gets a laugh track pic.twitter.com/BqkOEpzGw7

— Joe Buscaglia (@JoeBuscaglia) September 9, 2015

McCoy was injured in a practice against the Cleveland Browns on August 18, and had not been a full practice participant since then - until today, that is. It's also looking like all three of the Bills' backup running backs - rookie Karlos Williams, Bryce Brown, and Boobie Dixon - will be healthy for the opener, as well.